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The Advice Archive

Hormone Techniques

Trans men / Trans masculine

Oestrogen Blockers

Oestrogen blockers are entirely unnecessary for all but a very few people, most notably Trans children/preteens who are using them to avoid natural puberty until they reach an appropriate age to begin taking hormones (generally 13 or 14 at the youngest). You cannot take blockers for extended periods of time as it is unsafe for your system – you need to have some sex hormones in your body if you are in your teens or older. You have no need for oestrogen blockers if you’re on testosterone – it will shut down your ovaries, and therefore your oestrogen production, as long as your testosterone levels are above a certain minimum.

See here for more thoughts on oestrogen blockers.


Trans women / Trans feminine

Androgen Blockers


Cycling Versus Regularity

There are two distinct camps when it comes to discussions on how and when to take oestrogen tablets: cycling and regularity. Each system has its advantages and disadvantages, as described below.


The cycling technique gets its name from the way in which the dose of oestrogen and/or progesterone taken each day is changed over a set time-period before restarting. The basis of this is that a cisgender woman will find her levels of oestrogen and/or progrestrone change on a day-to-day basis and this technique attempts to replicate this hormone cycle in transwomen.

The advantages of the cycling technique are that a more female hormone cycle will be produced in the trans woman and it is also said to benefit breast growth; although no formal study has been undertaken in this.

The major disadvantage of the cycling technique is mood swings that develop due to the fluctuation in hormone levels. It can be very similar to PMT experienced by cisgender women.


The regularity technique gets its name from the way in which a set dose of oestrogen and/or progesterone is taken at certain points during the day. The basis of this technique is that part of the daily dose will be used to combat the day’s production of testosterone while the rest will be timed to fit in with the body’s production of growth hormone, which is produced while a person is sleeping and is linked to physical development and repair.

The advantages of the regularity technique are that the main dose of HRT is taken when the body is producing growth hormone, so feminisation should be accelerated; although no formal study has been undertaken in this.

The disadvantage of the regularity technique is that a relatively high dose of oestrogen is required for it to be effective, as the bulk is taken before going to bed so if a low dose is being used there is little left to combat the effects of the day’s testosterone.

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